Juventus's priority this summer is to bring in a top-level goalkeeper capable of staying in the squad alongside Mattia Perin, with Di Gregorio, who joined from Monza for €20m in 2024 after being named Serie A's best goalkeeper the previous season, having fallen short of expectations last season and been placed on the market as a result.
His agent's interview several weeks ago did little to calm the situation around him, and a sale now looks close to the only realistic outcome.
Luciano Spalletti nonetheless started him in the friendly defeat to Inter in Perth, a match in which he committed two errors, with the head coach later noting publicly that Di Gregorio could have done better with Inter's second goal.
According to gazzetta.it, the Premier League remains the most likely destination for the 28-year-old, but two other clubs have entered the picture in the past few hours, with Marseille and Valencia, of Ligue 1 and La Liga respectively, both making enquiries about the goalkeeper.
Di Gregorio made 30 Serie A appearances last season, keeping 13 clean sheets, a return that put him among the division's better performers on paper despite the underwhelming individual performances that have followed him into pre-season.
Juventus have also rejected an approach from Arsenal over a swap deal involving Kepa Arrizabalaga, preferring instead to pursue a straightforward sale, with the club keen to have a settled goalkeeping situation in place before the new Serie A season begins.