The Dutchman won the Premier League in his debut season at Anfield but endured a considerably tougher second campaign in charge.
Liverpool have replaced Slot with Andoni Iraola, who joins from Bournemouth.
Iraola did an outstanding job at the south coast club last season, guiding Bournemouth to a sixth-place finish that secured Champions League football for the club next season.
Liverpool have now confirmed on their official website that four members of staff are joining Iraola's coaching team.
Tommy Elphick and Shaun Cooper will both join as first-team coaches, the club confirmed. Pablo de la Torre arrives as assistant coach, while Tom Webber joins as tactical analyst for the first team.
All four have moved across from Bournemouth and worked alongside Iraola at the club between 2023 and 2026. Beyond his time at Bournemouth, Iraola has previously managed at Rayo Vallecano among other clubs during his coaching career.
Elphick, Cooper, de la Torre and Webber join at Anfield having built a strong understanding with Iraola over three years on the south coast, where Bournemouth established themselves as one of the Premier League's most consistent overachievers.
Liverpool's sporting director, Richard Hughes, previously worked with Iraola during his time at Bournemouth, a relationship that is understood to have played a role in the appointment.
The new-look coaching team represents a significant overhaul of Liverpool's backroom staff following Slot's exit, with the club looking to rebuild momentum after slipping from champions to a fifth-placed finish in the space of a single season. Iraola's appointment brings a fresh approach to Anfield, with the Spaniard having earned widespread praise for his work at Bournemouth, where he established the club as a consistent top-half Premier League side before his move to Merseyside.
Liverpool will be hoping the appointment can arrest last season's decline and restore the club to the level that delivered the title under Slot's stewardship.
The Reds' new season begins next month, with Iraola set to take charge of his first competitive fixture as the club looks to bounce back from a difficult second season under Slot's management.