The 16-year-old playmaker has already gained experience in men's football with Slavia Prague's second team, a factor that stood out to Bayern Munich's recruitment staff as they moved to secure his signature.
Michael Wiesinger, the club's head of sport and youth development, welcomed the arrival of the young Czech talent.
"We're delighted to have won Matous for FC Bayern. He is an interesting attacking talent, technically accomplished and a strong footballer, who has already gained experience in men's football with Slavia Prague's second team."
Srb's move continues Bayern's long-standing strategy of recruiting promising young talent from across Europe into their academy system, with the club hopeful that the playmaker can follow the path of previous imports who have progressed through the youth ranks towards first-team football in Munich.
His arrival adds further creative quality to Bayern's underage sides as the club continues to invest heavily in developing the next generation of talent within its academy structure.
The move represents a significant early step in Srb's career, taking him away from Slavia Prague - one of the Czech Republic's most successful clubs and a regular producer of talent for the national team - to one of European football's most prestigious academy environments.
Having already featured for Slavia's second team while still a schoolboy, the midfielder's early exposure to senior football was seen as a strong indicator of his readiness to make the step abroad at such a young age.
Bayern's youth development staff will now look to integrate Srb gradually into their age-group sides, with the club's structured pathway from the academy through to the first team continuing to attract some of the most sought-after teenage talents from leagues across the continent, including several nations in Central and Eastern Europe in recent years.