Only the formal signatures remain before the deal is completed, according to Romano, who confirmed the agreement on Friday.
Guagua has made 42 appearances for Independiente del Valle, who play in Ecuador's top flight, scoring four goals and adding five assists, and has already won two senior caps for Ecuador, though he was not part of the country's World Cup squad.
Independiente del Valle paid tribute to the midfielder before his final appearance for the club, in a 3-2 win over Delfín, with the club posting on social media: "The Valley of Dreams will always be your home."
Guagua, who came through Independiente's academy and made his senior debut for the club in 2025, is set to spend the coming season on loan at Mérida in Spain's Primera RFEF before making the move to Brentford proper, allowing him time to adjust to European football before a push for regular Premier League football.
Birmingham City had also been strongly linked with the midfielder in recent days, reportedly close to finalising a deal of their own, before Brentford entered the picture and moved decisively to secure his signature.
Guagua's rise in Ecuador was not without controversy: he was fast-tracked into the senior national team by then-coach Sebastián Beccacece in March 2025, featuring for around an hour in a goalless draw with Chile before he had even made his debut for Independiente del Valle's first team, a decision that drew criticism given his age and inexperience at club level.
The scrutiny that followed reportedly affected him mentally, with the club's directors at one stage citing his state of mind as a factor in team selection. The move to Brentford continues a recent pattern of English clubs recruiting young Ecuadorian talent as the country's academies increasingly attract attention from Europe.