The Catalan side are keen to strengthen their defence with young talent and are considering making another attempt to sign the 18-year-old after an approach last summer failed to produce an agreement.
Sport reports that sporting director Deco has returned to the possibility of recruiting Nijstad as Barcelona assess options to improve their defensive depth. The teenager is highly regarded by the club's recruitment department, which sees him as a potential long-term addition to Hansi Flick's squad.
Twente are understood to value the defender at approximately €20 million (£17.4m), a figure Barcelona consider excessive for a player of his age. The Dutch club are in a strong negotiating position, particularly after Nijstad signed a new contract running until 2029.
Barcelona are nevertheless weighing up whether to return with a proposal during the January transfer window. The club's interest has not disappeared despite the financial obstacle, and the defender remains one of the options being considered as they plan for the future of their back line.
Nijstad's profile fits Barcelona's strategy of recruiting promising young players who can develop into first-team regulars. His potential has attracted attention beyond Spain, but the Catalans are understood to be particularly keen on securing his signature.
The club are also monitoring other defensive candidates, meaning Nijstad is not the only route being explored. However, Sport's report suggests that he has become a serious target for the sporting department as Deco looks to provide Flick with additional defensive options.
One factor that could influence Barcelona's spending plans is the possibility of changes elsewhere in the squad. The future of Alejandro Balde has been raised as a potential consideration, with a departure potentially creating greater room for recruitment. However, no completed transfer or agreement involving the defender has been established.
The €20 million asking price remains the central difficulty. Barcelona are reluctant to meet Twente's valuation, while the Dutch club have little incentive to accept a reduced fee given the length of Nijstad's contract.
A January move is therefore far from straightforward. Barcelona must decide whether the teenager is worth the investment now or whether they should pursue alternative targets, while Twente will be aware that interest from a major European club could increase the defender's value.
For the moment, Nijstad remains a Twente player, with Barcelona's renewed interest indicating that the club have not abandoned their pursuit after the unsuccessful summer approach.